毛一雷，宁波人士，北京协和来自医院主任医师，教授，博李员础士生导师，曾留学美国哈佛大学、瑞典隆德大学获博士学位，现为中国医师协会肝脏外科宽阿争战交婷推干医师委员会副主任委员，全国卫生产业企业管理协会外科技术创新与推广分会会长 ，中华外科协会肝脏学组委员，中华肿瘤学会肝癌学组委员，中国抗癌协会肝癌专业委员会委员，卫生部肝癌规范诊疗专家组专家，乱仅请元海峡两岸卫生交流协会普通外科专家委员会常务委员，美国营养协会(ASN)会员，国际肝胆胰协会中国状析是案型硫分会委员 。擅长腹部外科、主要是肝、胆疾病的诊断和外科治疗，同时对外科疑难和重症360百科疾病的治疗、临床营养支持有较深的研究。20布离行14年被评为高正脚垂小修地要北京协和医院十大最佳外科教授。
1997年起在美国哈佛大学Joslin 研究中心做博士后研究，主要的方向是研究重症疾病、内毒素血症和激素的拮抗，激素的细胞内信号转导、作用途径及其调节因子等。并参与在国际上首先克隆了大鼠SOCS基因，多次在国际会议上发言。从1999年初起，在哈佛大学麻省总医院(MGH)肿瘤外科(Surgical Oncology，全美同类科室连续三年排名来自第一)做临床研究。曾被美国Li-Foundation Heritage Prize基金(California, U360百科SA)授于2000/2001年度的杰出成就奖，成为该年度生物医学界唯一获奖者。
1999年回国后，在带府思此较很游齐中国医学科学院，北京协和医院外科从事临床工作。主持多个临床相关的科研项目，分别申请到国际国大顾仅内研究基金数百万，主要研究包括"肝癌早期诊断血清标记物GP73在临床上的应用及其相关抗体的开发"和"新的肝功能评估走谈饭晚方法:GSA三维立体肝功能现象技术"，达国际先进水平。分别获国家癌症中心临床科研一等奖，卫生部医药卫生青年科技论坛湖获婷求密矿业附怀报纪一等奖， 2014年中华医学科技奖三等奖第一完成人视吧。
1990在澳大利亚Modbury医院完成住院医训即击阶花督谓革四练;1997年获北欧最著名的住记续瑞典隆德大学(Lund Uni又versity)外科博士学位，师从欧洲科学院院士、国际肝胆胰外科协会主席Stig Bengmark和欧洲外科研究协会主席Bengt Jeppsson。1999年在美国哈佛大学完成博士后训练，师从哈佛著名科学家Robert J. Smith;同时在美国麻省总医院(MGH)肿瘤外科完成临床培训。
2001年获美国"L案核站华器i-foundation Heritage Prize"杰出成就奖，成为该年度生物医学界唯一获奖者;曾连续三次(第五、第六、第七届)获全国还地克究居达胜投普外科中青年优秀论文一等奖，成为该奖项唯一一个连续三候季般次获一等奖者;从2000余年至今多次获北京协和医院医疗成果奖和优秀论文奖。2010年和2011年又分别荣死切接乎轻存局运减通获得卫生部第十届医药卫生青年科技论坛一等奖、中国国家癌症中心研究论文一等奖，2014反防灯影哪蒸再款品年获中华医学科技奖三等奖 。主持美国CMB基金、参与国家863项目、国家科技支撑计划课题及国家自然科学基金固算点织围理挥等多个项目。在国际、国内著名杂志发表100余篇论文，任国内11家核心杂志的副主编和编委。有国家专续及利两项。目前主持的"GP73斗件还市肝癌早期诊断"和"GSA肝脏三维立体肝功能评估"的项目处国内领先、国际先进地位。荣获2017年全国卫生计生系统先进工作者的荣誉 。
国内期上师尔族呀假根又培刊编委:
中华医学杂志，HBPD INT(SCI)，Chinese Medical Sciences Journal，Gastroenterology Report，中华普通外科杂志，中国医学科学院学报，中华消化外科杂志，中华内分泌外科杂志，中华临床营养杂志，中国实用外科杂志，中华临床医师杂志，中国普外基础与临床杂志，基础医学与临床，中国现代医生杂志编委
北京哈佛校友会(二、三、四届)理事
国际编委:Journal of Gastrointestinal Surgery
来自 第一作者、通讯作测奏准齐蛋老盟女裂概低者SCI文章
Shunda Du, Yilei Mao, Xinting Sang, Xin Lu, Zhiying Yang, Shouxian
Zhong, JIefu Huang. Bleeding Ectop360百科ics. The L唱地论老长够后却渐ancet, 20量裂华由诗而波题当球久10;375(9732): 21922192.
Yilei M要卷ao, Huayu Yang, Haifeng Xu, et al. Golgi protein 滑距皮73 (GOLPH2) is
a valuable serum mark for hepatocellular carcinoma. GUT.
2010, 59 (12):1687尼大愿视-1693.
Mao Y, 活红飞妈语执苦唱单Yu Z, Lu X, Sang X, Yang Z, Zhong S. Survival after 90%
hepatectomy in rat: blocking Jak-Stat or p21-ras signaling. Hepatology, 2004;40 (4 suppl 1): 175A.
口算观现 Mao Y, Nobae弦按k S, Kasravi B, Adawi D, Stenram U, Molin G, Jeppsson B. 除成设许维点功济理交The effects ofLactobacil严者晶把lusstrains and oat fiber on methotrexate-induced enterocolitis in rats. Gastroenterology 1996; 叶支沉煤准又扬煤每111: 334-344.
Xinting Sang, Yongliang Sun, Yilei Mao,Zhiying Yang, Xin Lu, Huayu Yang, Haifeng Xu, Shouxian Zhong, Jiefu Huang. Hepatobiliary Cystadenomas and Cystadenocarcinomas: Report of 33 Cases. Liver Internati企onal, 2011; 31(9):1337-1连对粉344.
Sun YL, Yang H, Mao Y,et al. Th史比许e Increased 虽应候题械GP73 Expression 单达造in Hepatocellula爱百r Carcinoma Tissue Correlates to the Tumor Aggression but not Survival. J Gastroenterol Hepatol, 2011;26:1207-1212.
Mao Y. Ling P-R, Fitzgibbons TP, McCowen KC, Frick GP, Bistrian BR, Smith RJ. Endotoxin-Induced Inhibition of Growth Hormone Receptor Signaling in Rat Liverin Vivo.Endocrinology 1999, 140: 5505-5515.
Huayu Yang, Yilei Mao, Xin Lu, et al. The Effects of Urinary Trypsin Inhibitor on Liver Function and Inflammatory Factors in Patients Undergone Hepatectomy: a Prospective, Randomized, Controlled Clinical Study. Am J Surg, 2011, 202(2):151-157.
Mao Y, Nobaek S, Adawi D, Molin G, Jeppsson B. Comparison of the effects of different strains ofLactobacillusin reducing bacterial translocation on methotrexate induced-enterocolitis in rats. Digestive surgery 1997; 14: 284-291.
Mao Y,Huang J. Commentary on: Aspartate transaminase to platelet ratio index (APRI): A simple noninvasive index assessing liver fibrosis in patients with chronic liver diseases. Hepat Mon. 2011;11(5):376-377.
Mao Y, Yu J-L, Ljungh Å, Molin G, Jeppsson B. Intestinal immune response to oral administration ofLactobacillus reuteriR2LC,Lactobacillus plantarumDSM 9843, pectin and oatbase on methotrexate-induced enterocolitis in rats. Microbial Ecology in Health and Disease 1996; 9: 261-270.
Mao Y, Kasravi B, Nobaek S, Wang L-Q, Adawi D, Roos G, Stenram U, Molin G, Bengmark S, Jeppsson B. Pectin-supplemented enteral diet reduces the severity of methotrexate-induced enterocolitis in rats. Scand J Gastroenterology 1996; 31: 558-567.
Shunda Du, Yilei Mao, Xin Lu, Xinting Sang, Shouxian Zhong, Jiefu Huang. Hepatic Metastatic Melanoma: Diagnosis and Treatment. Brazilian Journal of Medical and Biological Research 2012XU Haifeng, MAO Yilei,DU Shunda, CHI Tianyi, LU Xin, YANG Zhiying, SANG Xinting, ZHONG Shouxian, HUANG Jiefu. Adult primary undifferentiated embryonal sarcoma of the liver: A case report. Chin Med J, 2010, 123(2): 250-252.
Liu Liguo, Xu Yiyao, Mao Yilei, Sang Xinting, Yang Zhiying, Lu Xin, Zhong Shouxian, Huang Jiefu. Adult congenital diaphragmatic hernia of the liver: a rare case report. Science China-Life Sciences, 2010; 53 (2): 204-206.
Ge PL, Du SD, Mao YL. Advances in preoperative assessment of liver function. HBPD INT, 2014;13(4):361-370.
Mao Y, Du S, Ba J, Li F, Yang H, Lu X, Sang X, Li S, Che L, Tong J, Xu Y, Xu H, Zhao H, Chi T, Liu F, Du Y, Zhang X, Wang X, Dong J, Zhong S, Huang J, Yu Y, Wang J. Using Dynamic99mTc-GSA SPECT/CT Fusion Images for Hepatectomy Planning and Postoperative Liver Failure Prediction.Ann Surg Oncol, 2014 Oct 8.
Du S, Wang Z, Sang X, Lu X, Zheng Y, Xu H, Xu Y, Chi T, Zhao H, Wang W, Cui Q, Zhong S, Huang J, Mao Y. Surgical resection improves the outcome of the patients with neuroendocrine tumor liver metastases: large data from Asia. Medicine. (Dec 2, 2014 Accept)
GE P, DU S, MAO Y: Advances in preoperative assessment of liver function. Hepatobiliary Pancreat Dis Int 2014; 13(4): 361-370
PAN J, ZHANG Y, YANG H, XU H, LU X, SANG X, ZHONG S, MAO Y: The response of Golgi protein 73 to transcatheter arterial chemoembolization in patients with hepatocellular carcinoma may relate to the influence of certain chemotherapeutics. Hepatobiliary Pancreat Dis Int 2015; 14(4): 406-412
LIAO W, MAO Y, GE P, YANG H, XU H, LU X, SANG X, ZHONG S: Value of quantitative and qualitative analyses of circulating cell-free DNA as diagnostic tools for hepatocellular carcinoma. Medicine 2015; 94(14): e722
YANG H, FU Q, LIU C, LI T, WANG Y, ZHANG H, LU X, SANG X, ZHONG S, HUANG J, MAO Y: Hepatitis B virus promotes autophagic degradation but not replication in autophagosome. BioScience Trends 2015; 9(2): 111-116
DU S, WANG Z, SANG X, LU X, ZHENG Y, XU H, XU Y, CHI T, ZHAO H, WANG W, CUI Q, ZHONG S, HUANG J, MAO Y: Surgical resection improves the outcome of the patients with neuroendocrine tumor liver metastases. Medicine 2015; 94(2): e388
TANG G, YANG H, ZHANG J, REN J, SANG X, LU X, ZHONG S, MAO Y: Magnesium isoglycyrrhizinate inhibits inflammatory response through STAT3 pathway to protect remnant liver function. World Journal of Gastroenterology 2015; 21(43): 12370-12380
DU S, NI J, WENG L, MA F, LI S, WANG W, SANG X, LU X, ZHONG S, MAO Y: Aggressive locoregional treatment improves the outcome of liver metastases from grade 3 gastroenteropancreatic neuroendocrine tumors. Medicine 2015; 94(34): e1429
HUANG J, MILLIS J, MAO Y, MILLIS M, SANG X, ZHONG S: Voluntary organ donation system adapted to Chinese cultural values and social reality. Liver Transplantation 2015; 21: 419-422
MAO Y, DU S, BA J, LI F, YANG H, LU X, SANG X, LI S, CHE L, TONG J, XU Y, XU H, ZHAO H, CHI T, LIU F, DU Y, ZHANG X, WANG X, DONG J, ZHONG S, HUANG J, YU Y, WANG J: Using dynamic Tc-GSA SPECT/CT fusion images for hepatectomy planning and postoperative liver failure prediction. Ann Surg Oncol 2015; 22: 1301-1307
Liao W, Yang H, Xu H, Wang Y, Ge P, Ren J, Xu W, Lu X, Sang X, Zhong S, Zhang H, Mao Y. Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing. Oncotarget. 2016; 7(26): 40481-40490.
Xu W, Xu H, Yang H, Liao W, Ge P, Ren J, Sang X, Lu X, Zhong S, Mao Y. Continuous Pringle maneuver does not affect outcomes of patients with hepatocellular carcinoma after curative resection. Asia Pac J Clin Oncol. 2016 Aug 12. doi: 10.1111/ajco.12585. [Epub ahead of print]
Xu W, Liao W, Ge P, Ren J, Xu H, Yang H, Sang X, Lu X, Mao Y. Multiple Primary Malignancies in Patients With Hepatocellular Carcinoma: A Largest Series With 26-Year Follow-Up. Medicine (Baltimore). 2016; 95(17): e3491.
Xu W, Ge P, Liao W, Ren J, Yang H, Xu H, Sang X, Lu X, Zhong S, Mao Y. Edmondson grade predicts survival of patients with primary clear cell carcinoma of liver after curative resection: A retrospective study with long-term follow-up. Asia Pac J Clin Oncol. 2016 Apr 21. doi: 10.1111/ajco.12494. [Epub ahead of print]
Du S, Liu G, Cheng X, Li Y, Wang Q, Li J, Lu X, Zheng Y, Xu H, Chi T, Zhao H, Xu Y, Sang X, Zhong S, Mao Y. Differential Diagnosis of Immunoglobulin G4-associated Cholangitis From Cholangiocarcinoma. J Clin Gastroenterol. 2016; 50(6): 501-5.
非第一作者SCI文章:
Huang JF, Mao YL, Millis JM. Government policy and organ
transplantation in China. The Lancet; 2008; 372(9654): 1937-1938.
Jiefu Huang, J. Michael Millis, Yilei Mao, M. Andrew Millis, Xinting Sang,
Shouxian Zhong. China's Pilot Program of Organ Donation from Patients
following Cardiac Death.The Lancet; 2011; in press
Miao RY, Zhao HT, Yang HY,Mao YL, Lu X, Zhao Y, Liu CN, Zhong SX, Sang XT, Huang JF. Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: A meta-analysis. World J Gastroenterol, 2010;16(23): 2931-2942.
Sang XT, Zhao HT, Lu X, Mao YL, Miao RY, Yang HY, Yang YF, Huang JF, Zhong SX. Prediction and identification of tumor-specific noncoding RNAs from human UniGene. Med Oncol, 2010;27(3):894-898
Millis JM, Huang J, Millis MA, Liu Y, Y. Mao, and M. Simmerling. 2007: The Year of Regulatory Change. Transplantation Proceedings, 2009;41:25–26.
Lu X, Zhao HT, Yang HY, Mao YL, Sang MT, Miao RY, Xu YY, Du SD, Xu HF, Chi TY, Yang ZY, Zhong SX, Huang JF. A Prospective Clinical Study on Early Recurrence of Hepatocellular Carcinoma After Hepatectomy. J Surg Oncol, 2009;100(6):488-493.
Lu X, Zhao H, Yang H, Mao Y, Sang X, Miao R, Xu Y, Du S, Xu H, Chi T, Yang Z, Zhong S, Huang J. A prospective clinical study on early recurrence of hepatocellular carcinoma after hepatectomy. J Surg Oncol 2009;Jiefu Huang, Yilei Mao, Yu Wang, Zongjiu Zhang, Minggang Zhao, Yong Liu. Modernazation of the organ transplantation program in China. Transplantaion, 2008;86(12):1649-1652.
Shao Y, Sun ZY, Sun SW, Zhao Y, Sin WY, Yuan YH, Simpson, AJ, Old LJ, Sang XT, Mao YL,Xie Y, Huang JF, Zhao HT. Identification and expression analysis of novel LAGE-1 alleles with single nucleotide polymorphisms in cancer patients. J Cancer Res Clin Oncol. 2008; 134(4): 495-502.
Ni XG, Bai XF, Mao YL, Shao YF, Wu JX, Shan Y, Wang CF, Wang J, Tian YT, Liu Q, Xu DK, Zhao P. The clinical value of serum CEA, CA19-9, and CA242 in the diagnosis and prognosis of pancreatic cancer. Eur J Surg Oncol, 2005; (2)31:164-169.
Ling PR, Smith RJ, Mueller C, Mao Y,Bistrian BR. Inhibition of interleukin-6-activated janus kinases/signal transducers activators of transcription but not mitogen-activated protein kinase signaling in liver of endotoxin-treated rats. Crit Care Med 2002;30:202-211.
McCowen KC, Ling P, Ciccarone A, Mao Y, Chow JC, Bistrian BR, Smith RJ. Sustained endotoxemia leads to marked down-regulation of early steps in the insulin-signaling cascade. Critical Care Medicine, 2001;29:839-846.
Liu Q, Nobaek S, Adawi D, Mao Y,Wang M, Molin G, Ekelund M, Jeppsson B. Aministration of Lactobacillus plantarum 299v reduces side-effects of external radiation on colon anastomotic healing in an experimental model. Colorectal Disease. 2001;3:245-252.
非医学作品
2008年底随中国南极科考队前往南极探险。著有《冰雪世界的远征》一书。
2013年在美国Xlibris出版社出版了《TheTop of the Bottom of the World》。
国际交流
国外学习
非医疗活动
腹部外科重症疾病、肝胆外科疾病，尤其在肝脏疾病的诊治方面
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